Two sample MR report
PARK7_T Proliferating against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.8968624 | 1.8640940 | 0.7145181 |
| Weighted median | 3 | 0.1702956 | 0.0809252 | 0.0353472 |
| Inverse variance weighted | 3 | 0.1594496 | 0.0626090 | 0.0108731 |
| Simple mode | 3 | 0.1817505 | 0.0903350 | 0.1818855 |
| Weighted mode | 3 | 0.1807663 | 0.0871723 | 0.1738375 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1768677 | 1 | 0.6740791 |
| Inverse variance weighted | 0.3335341 | 2 | 0.8463968 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.2192477 | 0.5539201 | 0.7600643 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.38e-05 | 0 | TRUE | 0.5826937 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
